her effect activates in the damage step, so i dont see why not, costly combo to pull off though, since it'll cost you at least four cards to do and two thousand life points. since you'll need a monster to tribute for cybernic magaican, lily, a discard and the magicain himself. plus with a claer feild if your hoping to get a good shot at the oppoents life points.
so yeah by all means go for, it, it'll just probably need a deck built around that effect to work well.